Among the many types of antidepressants, Selective Serotonin Reuptake Inhibitors (SSIR’s) are the most commonly prescribed. They work by inhibiting the reuptake of serotonin into presynaptic cells, thus raising the serotonin levels in the synaptic cleft accessible for the postsynaptic receptors to bind. Because of the change in the balance of serotonin in the brain, the patient then experiences a boost in mood. SSRI’s generally affect the serotonin and not other neurotransmitters in the brain, which is the reason why it is called selective.
The Food and Drug Administration has approved various types of SSRI’s for treating depression, anxiety disorders, and certain personality disorders. These prescriptions can help manage and control symptoms of moderate to severe depression, are generally safe, and are less likely to cause side effects compared to other antidepressants. One of the popular SSRI’s in the market is Celexa, with the generic name of Citalopram.
Celexa (citalopram hydrobromide) is approved by the FDA for treatment of major depression, although it can also be given to patients with Obsessive Compulsive Disorders, panic and anxiety disorders, Posttraumatic Stress disorders, and even Premenstrual Dysphoric Disorder. It has been approved for use in 1998. Among the common (and mild) side effects of taking Celexa is having dry mouth, experiencing nausea, headaches, tremors, insomnia, excessive sweating, and vomiting, among others. Withdrawal symptoms can also happen to patients who have stopped taking Celexa.
Patients who are taking Celexa run the risk of developing serious side effects such as muscle stiffness/rigidity, overactive reflexes, high fever, tremors, and fast or uneven heartbeats. Doctors advise their patients to report adverse side effects such as hallucination, lower sexual drive or changes in sexual abilities, loss of coordination, black stools, and vomits that look like coffee grounds. If these side effects continue or worsen, inform your pharmacist or doctor immediately. Doctors also warn women who are pregnant (particularly those who are in their third trimester), planning to get pregnant, or are breastfeeding: taking Celexa can cause adverse effects and health complications to their infants.Read More